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Supplemental Biologics License Application for Brentuximab Vedotin in Frontline Advanced Hodgkin...

Based on positive results from the Phase III ECHELON-1 Clinical Trial evaluating brentuximab vedotin (Adcetris®; Seattle Genetics) in combination with chemotherapy for the frontline...
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Phase Ib Trial of Enfortumab Vedotin + Immune Checkpoint Inhibitor Initiated...

Seattle Genetics and Astellas Pharma confirmed the dosing of the first patient in EV-103, a phase Ib clinical trial evaluating the safety and tolerability...

Combination of SGN-LIV1A + Pembrolizumab to be Investigated as First Line...

Breast cancer is a cancer which forms in breast tissue. Metastatic breast cancer occurs when the cancer has spread to other parts of the...

Phase II Trial of Tisotumab Vedotin in Advanced Cervical Cancer Provides...

Genmab and Seattle Genetics confirmed their decision to start a Phase II study of tisotumab vedotin in patients with recurrent and/or metastatic cervical cancer....

Tisotumab vedotin Demonstrates Encouraging Response Rate and a Manageable Safety Profile...

Preliminary clinical data for tisotumab vedotin, also known as HuMax®-TF-ADC from a Genmab-sponsored phase I/II clinical trial (GEN 701) were featured today in an...

Seattle Genetics to Co-develop Tisotumab Vedodin with Genmab for the Treatment...

Genmab, an international biotechnology company headquartered in Copenhagen, Denmark, and Seattle Genetics, confirmed that Seattle Genetics has exercised its option to co-develop tisotumab vedotin. The...

Seattle Genetics buys Bristol-Myers Squibb’s Pharmaceutical Manufacturing Facility in Bothell, Washington

Seattle Genetics has agreed to purchase Bristol-Myers Squibb's pharmaceutical manufacturing facility in the North Creek area of Bothell, WA, a short drive from Seattle....

Winding-Down of Research Operations but Astellas Retains Promising Antibody-Drug Conjugate R&D...

In a surprise move to most, but expected by industry insiders, Astellas Pharma, a Japan-based company focusing on the development of novel treatments in Urology,...

Brentuximab Vedotin Approved by Health Canada for Post-ASCT Consolidation Treatment of...

Health Canada, the federal department responsible for helping Canadians maintain and improve their health, has issued a non-conditional marketing authorization for use of brentuximab...

Antibody-drug Conjugates: Technologies and Global Markets

Less than 3 decades old, antibody-drug conjugate or ADC-technology is a relatively new.  Due to many technological advances, recognition of appropriate target antigens, success...