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Tag: Lymphoma

Phase I Study Supports Therapeutic Potential of Polatuzumab Vedotin in non-Hodgkin...

Lymphoma - with its main forms Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) - is the most common blood cancer which occurs when cells...

Supplemental BLA for Brentuximab Vedotin in Post-Transplant Hodgkin Lymphoma Patients at...

Based on positive data from the Phase III AETHERA trial (SGN35-005; NCT01100502) of brentuximab vedotin (Adcetris®; Seattle Genetics, Inc/Takeda Oncology) as consolidation therapy immediately following...
ASCO 50th Annual Meeting

Results from Phase I Trial with SGN-CD19A Shows Encouraging Anti-tumor Activity...

esults from an interim phase I clinical trial presented at the 50th Annual Meeting of the American Association of Clinical Oncology (ASCO), being held May 30 - June 3, 2014 in Chicago, Ill, shows that SGN-CD19A (Seattle Genetics, Inc, Bothell, WA 98021, USA), an antibody-drug conjugate or ADC in development for the treatment of B-cell malignancies, offers encouraging anti-tumore activity in patients with Non-Hodgkin Lymphoma (NHL).[1]

Trial Shows 92% Objective Response Rate in the Evaluation of Brentuximab...

Data presented at the 2014 Annual Bone Marrow Transplant (BMT) Tandem Meetings organized by The American Society for Blood and Marrow Transplantation and the Center for International Blood & Marrow Transplant Research being held in Grapevine (Dallas), Texas, February 26 - March 2, 2014, highlights the benefits of brentuximab vedotin (Adcetris®; Seattle Genetics) in various treatment schedules for hard to treat cancers.
Leukemia

Ongoing Phase I Clinical Trial of SGN-CD19A Demonstrates Encouraging Activity and...

Phase I interim data from a clinical trial with SGN-CD19A being developed for the treatment of B-cell malignancies, including acute lymphoblastic leukemia or ALL -- shows...

Phase I Trial of Loaded Antibody Establishes Dose, Catalogues Side Effects...

An antibody loaded with an anti-cancer agent produced complete or partial remissions in 38% of patients with relapsed or therapy-resistant Hodgkin lymphoma enrolled in...

Pivotal Trial In Relapsed And Refractory Hodgkin Lymphoma Shows Positive Results...

Results of a pivotal clinical trial with of single-agent brentuximab vedotin (SGN-35), an antibody-drug conjugate (ADC) targeted to CD30 shows that the trial drug...