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Study Shows Concentration of Intratumoral Payload Correlates with ADC Activity

A study published in the March 2018 edition of Molecular Cancer Therapeutics shows that, while antibody–drug conjugates or ADC have become important scaffolds for...

IMGN779 Induces DNA Damage, Cell Cycle Arrest, and Apoptosis in AML...

CD33 is broadly expressed on leukemic blasts of patients with acute myeloid leukemia.  Although nearly 80% of patients show a high initial response rates to chemotherapy, many...