Home Tags DNA-crosslinking agents

Tag: DNA-crosslinking agents

Featured Image: ADC Therapeutics Booth at AACR 2018 Courtesy: © 2017 – 2018. Sunvalley Communication, LLC / Evan Wendt. Used with permission.

Pivotal Phase II Clinical Trial of Single Agent Loncastuximab Tesirine in...

Results from a pivotal 145-patient Phase II clinical trial of loncastuximab tesirine (ADCT-402; ADC Therapeutics) for the treatment of relapsed or refractory diffuse large...

What is Pyrrolobenzodiazepine (PBD)?

Pyrrolobenzodiazepine (PBD) Chemical Name: Diazepinoindole; Molecular Formula: C14H14N2O3 Molecular weight: 258,27 g/mole Average mass: 181.193 Da Monoisotopic mass: 181.063995 Da Introduction Discovered in 1963, the pyrrolobenzodiazepines (PBDs) are a class of antitumor antibiotics...

X