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Drug-detached Naked Antibody Impairs ADC Efficacy

Abstract Armed with cytotoxic payloads, antibody-drug conjugate (ADC) becomes able to kill its naked-antibody-resistant tumor cell. When ADC circulates in the plasma, complete detachment of...

Data Confirms STRO-001 Eradicates B-Cell Hematologic Malignancies and Prolongs Survival

STRO-001, an antibody-drug conjugate or ADC targeting the CD74 cell surface protein in hematologic B-cell malignancies, being developed by Sutro Biopharma, has shown to...