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Pivotal Trial with Vadastuximab Talirine Initiated for Treatment of Patients with...

A phase III study called CASCADE, designed to evaluate Seattle Genetics' vadastuximab talirine (SGN-CD33A; 33A) in combination with azacitidine (Vidaza) or decitabine (Dacogen) has...

IMGN779 Induces DNA Damage, Cell Cycle Arrest, and Apoptosis in AML...

CD33 is broadly expressed on leukemic blasts of patients with acute myeloid leukemia.  Although nearly 80% of patients show a high initial response rates to chemotherapy, many...

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