Home Tags Mesothelin

Tag: mesothelin

RemeGen’s RC88 Receives US FDA Fast Track Designation

The United States Food and Drug Administration has granted Fast Track Designation for China-based RemeGen's RC88, a mesothelin (MSLN)-targeting antibody-drug conjugate (ADC). The investigational drug is intended for the treatment of patients diagnosed with platinum-resistant recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancers.

Anetumab Ravtansine Demonstrates Encouraging Preliminary Antitumor Activity in Heavily Pretreated Mesothelin-expressing...

In a phase I clinical trial, the investigational antibody-drug conjugate (ADC) anetumab ravtansine (BAY 94-9343; Bayer) shows promising antitumor activity in heavily pretreated patients with...

Study Confirms DMOT4039A Shows Anticancer Activity in Patients with Pancreatic or...

A study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) being held May 30 - June 3, 2014 in Chicago, Ill, describes the results of a phase I clinical trial of the investigational agent DMOT4039A against pancreatic and ovarian cancers. In this early clinical trial with the goal of identifying possible risks and defining likely dosages, the drug was well tolerated and in some patients showed initial evidence of anti-cancer activity.

X