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Innate Pharma Confirms Securing Investment to Develop Novel ADC

The French biotechnology company Innate Pharma, which focuses on the discovery as well as the development and commercialization of novel therapeutic antibodies-based therapeutics to...

Site-specific Conjugation Based on Bacterial Transglutaminase Shows Improved Therapeutic Index of...

The key conclusion of these posters is that ADCs generated by BTG-ADC have improved pharmacokinetics and show a beter therapeutic index in in vivo models compared to brentuximab, with a significantly higher maximum tolerated dose (>60mg/kg vs 18 mg/kg) and a higher specific tumoral uptake.