Tag: hydrophobic
A Novel Platform for the Generation of Site-Specific Antibody−drug Conjugates
Antibody-drug conjugates (ADCs) combine the superior selectivity of antibodies with the high potency of cytotoxic agents. With 9 approved and commercially available ADCs for...
Site Specific Conjugation of Hydrophobic Payloads Without Genetic Engineering
Site-specific conjugation leads to more homogeneous conjugates and allows control of the site of drug attachment. This approach frequently relies on antibody engineering to...