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A Novel Platform for the Generation of Site-Specific Antibody−drug Conjugates

Antibody-drug conjugates (ADCs) combine the superior selectivity of antibodies with the high potency of cytotoxic agents. With 9 approved and commercially available ADCs for...
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Site Specific Conjugation of Hydrophobic Payloads Without Genetic Engineering

Site-specific conjugation leads to more homogeneous conjugates and allows control of the site of drug attachment. This approach frequently relies on antibody engineering to...