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Tag: Fam-trastuzumab deruxtecan-nxki

HER2, Trastuzumab and the Development of Novel Antibody-drug Conjugates

In the mid-1970s, scientists discovered that certain genes, when mutated, can cause cancer.  Based on this observation they theorized that by targeting these oncogenes,...

HER2-targeting Trastuzumab Deruxtecan Shows Promise in Patients with Non-breast/Gastric Cancers

Results from a phase I study investigating fam-trastuzumab deruxtecan-nxki (formerly known as DS-8201a; Enhertu®; Daiichi Sankyo and AstraZeneca) showed signs of clinical activity of...

FDA Approves Trastuzumab Deruxtecan for Unresectable or Metastatic HER2-positive Breast Cancer

The U.S. Food and Drug Administration (FDA) has approved fam-trastuzumab deruxtecan-nxki (Enhertu®; Daiichi Sankyo and AstraZeneca)*, a HER2 directed antibody-drug conjugate or ADC, for...

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