Tag: Rovalpituzumab Tesirine
Zocilurtatug Pelitecan Shows Clinical Benefit as a Potential First-in-Class DLL3-Targeted ADC...
Updated data from the global Phase 1 clinical trial of zocilurtatug pelitecan (zoci; formerly known as ZL-1310; see ADC Drugmap; NCT06179069)* an antibody-drug conjugate...
AbbVie Discontinues Research and Development Program for Rovalpituzumab Tesirine
MERU, a Phase III trial evaluating rovalpituzumab tesirine (Rova-T / SC16LD6.5; AbbVie) as a first-line maintenance therapy for advanced small-cell lung cancer (SCLC), demonstrated...
Independent Data Monitoring Committee Recommends Enrollment to be Stopped for Study...
An Independent Data Monitoring Committee (IDMC) responsible for ongoing review of study data of the TAHOE study, a Phase III study evaluating Rovalpituzumab Tesirine...
Researchers Find SCLC-biopsy Specimen Reliable for Evaluating DLL3 Expression
High levels of delta-like protein 3 or DLL3 in small-cell lung cancer or SCLC are correlated with poor survival trends. Li-Xu Yan, MD, a...
First Patient with Advanced Solid Tumors with HER2 Expression Dosed in...
A first patient with advanced solid tumors with HER2 Expression was dosed in a phase I clinical trial with ADCT-502. The investigational drug being...
What to Expect at the 17th World Conference on Lung Cancer
An estimated 225,000 Americans are expected to be diagnosed with lung cancer this year. Recurrent Small Cell Lung Cancer or accounts for 10%...
Rovalpituzumab tesirine: Most Promising Clinical Candidate
Rovalpituzumab tesirine, also known as Rova-T, an antibody-drug conjugate being developed by AbbVie/Stemcentrx was recognized at the 7th Annual World Antibody Drug Conjugate (ADC)...
Collaboration to Explore the Safety and Efficacy of Combining Rova-T +...
A new Phase I/II clinical program in which Bristol-Myers Squibb collaborates with AbbVie will evaluate the safety, tolerability and efficacy of the investigational biomarker-specific...
Bio International: Innovation Driving Growth in the Biopharmaceutical Market
With our increasing understanding of disease mechanisms and our ability to unlock the power of the immune system to break significant barriers and change...
Rovalpituzumab Tesirine Shows Early Promise in Small Cell Lung Cancer
Rovalpituzumab tesirine (Rova-T or SC16LD6.5; AbbVie), a novel biomarker-specific 'smart-bomb' antibody-drug conjugate or ADC targeting the delta-like protein 3 or DLL3 protein, expressed in more...
