Tag: Rova-T
AbbVie Discontinues Research and Development Program for Rovalpituzumab Tesirine
MERU, a Phase III trial evaluating rovalpituzumab tesirine (Rova-T / SC16LD6.5; AbbVie) as a first-line maintenance therapy for advanced small-cell lung cancer (SCLC), demonstrated...
Independent Data Monitoring Committee Recommends Enrollment to be Stopped for Study...
An Independent Data Monitoring Committee (IDMC) responsible for ongoing review of study data of the TAHOE study, a Phase III study evaluating Rovalpituzumab Tesirine...
Phase II Study Evaluating Rovalpituzumab Tesirine Announced – AbbVie will Not...
After consulting with the U.S. Food and Drug Administration (FDA), AbbVie, a global research and development-based biopharmaceutical company, announced that the company will not...
Antibody-drug Conjugates: Technologies and Global Markets
Less than 3 decades old, antibody-drug conjugate or ADC-technology is a relatively new. Due to many technological advances, recognition of appropriate target antigens, success...
What to Expect at the 17th World Conference on Lung Cancer
An estimated 225,000 Americans are expected to be diagnosed with lung cancer this year. Recurrent Small Cell Lung Cancer or accounts for 10%...
Rovalpituzumab tesirine: Most Promising Clinical Candidate
Rovalpituzumab tesirine, also known as Rova-T, an antibody-drug conjugate being developed by AbbVie/Stemcentrx was recognized at the 7th Annual World Antibody Drug Conjugate (ADC)...
Collaboration to Explore the Safety and Efficacy of Combining Rova-T +...
A new Phase I/II clinical program in which Bristol-Myers Squibb collaborates with AbbVie will evaluate the safety, tolerability and efficacy of the investigational biomarker-specific...
Bio International: Innovation Driving Growth in the Biopharmaceutical Market
With our increasing understanding of disease mechanisms and our ability to unlock the power of the immune system to break significant barriers and change...
Rovalpituzumab Tesirine Shows Early Promise in Small Cell Lung Cancer
Rovalpituzumab tesirine (Rova-T or SC16LD6.5; AbbVie), a novel biomarker-specific 'smart-bomb' antibody-drug conjugate or ADC targeting the delta-like protein 3 or DLL3 protein, expressed in more...
AbbVie Demonstrates Progress in Oncology Research at ASCO 2016
Chemotherapy remains the standard of care in the treatment of many types of cancer. However, one of the problems with chemotherapeutics is that it...