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First Patient Dosed with PRO1184 and PRO1160 Cleared for Study Initiation...

Dosing has initiated in the Phase 1 first-in-human clinical trial of PRO1184 (NCT05579366),  an antibody-drug conjugates or ADC being developed by ProfoundBio comprising a folate receptor alpha-directed antibody conjugated to the exatecan payload using a novel, proprietary hydrophilic linker.

Novel Linker-Drug Technology Enables Antibody-Drug Conjugates with an Expanded Therapeutic Window

Preclinical data from a novel, proprietary ADC technology platform being developed by ProfoundBio was being presented at the 2021 Molecular Targets and Cancer Therapeutics...