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What to Expect at ASCO 2026: Next-Generation ADCs and T-cell Engagers...

This year, the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting will feature a breadth of new data on emerging antibody-drug conjugates (ADCs) and T-cell engagers (TCEs), particularly across solid tumors and hematologic malignancies. This article synthesizes pivotal findings from AbbVie’s next-generation ADC and TCE platforms—including SEZ6-, PSMA/STEAP1-, c-Met-, and FRα-targeted ADCs—alongside immune checkpoint inhibitor combinations and real-world evidence.

AbbVie Showcases Promising Phase 2 Data for Mirvetuximab Soravtansine in Platinum-Sensitive...

AbbVie Showcases Promising Phase 2 Data for Mirvetuximab Soravtansine in Platinum-Sensitive Ovarian Cancer at SGO 2026

Economy: Failure to Reshore Pharmaceutical Manufacturing: US Approved Drug Manufacturing Shifts...

Economy: Failure to Reshore Pharmaceutical Manufacturing: US Approved Drug Manufacturing Shifts to Europe as US Deal Volume Drops

ESMO 2025: TUB-040 Shows Robust Clinical Activity in Platinum-Resistant Ovarian Cancer

Positive early clinical data from the NAPISTAR1-01 Phase 2/2a study (NCT06303505) investigating TUB-040, an antibody-drug conjugates (ADC) being developed by Tubulis, were presented in a late-breaking oral presentation at the European Society for Medical Oncology (ESMO) Congress, held October 17 - 21, 2025 in Berlin, Germany.[1] (see ADC Drugmap).

Mirvetuximab Soravtansine Demonstrates Consistent Survival Benefit in Long-Term Analysis for Certain...

The final analysis of the confirmatory Phase 3 MIRASOL trial (NCT04209855) evaluating the efficacy and safety of mirvetuximab soravtansine (Elahere®; AbbVie - see Drugmap)*...

European Commission Approves Mirvetuximab Soravtansine for the Treatment of Platinum-Resistant Ovarian...

The European Commission has granted marketing authorization for mirvetuximab soravtansine (Elahere®; AbbVie/ImmunoGen) for the treatment of adult patients with folate receptor-alpha (FRα) positive, platinum-resistant high-grade serous epithelial ovarian, fallopian tube or primary peritoneal cancer who have received one to three prior systemic treatment regimens.
Photo: AbbVie R&D has focused on developing biologics. In particular, antibody therapeutics have been proven to be clinically effective for disease areas such as oncology and immunology. Photo courtesy: © 2019 - 2020 AbbVie

ESMO 2024: Showcasing Advancement in ADC Development Pipline with New...

During the upcoming European Society for Medical Oncology (ESMO) Congress being held in Barcelona, September 13-17, 2024, expect presentations to include new data on...
Photo: AbbVie R&D has focused on developing biologics. In particular, antibody therapeutics have been proven to be clinically effective for disease areas such as oncology and immunology. Photo courtesy: © 2019 - 2020 AbbVie

ASCO 2024: AbbVie to Showcases Robust Solid Tumor Pipeline with New...

New data from AbbVie's innovative antibody-drug conjugate (ADC) platform will be showcased across three oral presentations at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting (May 31 - June 4, 2024).

Paving the Way: Mirvetuximab Soravtansine + Pembrolizumab in Endometrial Cancer

At the recently held annual meeting of the American Association for Cancer Research (AACR), positive Phase 2 trial (NCT03835819) results of the combination of mirvetuximab soravtansine and the immune checkpoint inhibitor (ICI) Pembrolizumab (Keytruda®; Merck & Co) in the treatment of folate receptor-alpha (FR-α) positive recurrent microsatellite stable / mismatch repair proficient serous endometrial cancer were presented.

Creating A Strong ADC Pipeline: AbbVie Agrees to Acquires ImmunoGen for...

Creating A Strong ADC Pipeline: AbbVie Agrees to Acquires ImmunoGen for $10.1 Billion