Study Title
A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma (NCT01421667)

Trial description
This is an open-label, multicenter, phase II clinical trial to evaluate the efficacy and safety of brentuximab vedotin as a single agent in patients with CD30-positive non-Hodgkin lymphoma (NHL) (Part A). The study will also evaluate the safety and efficacy of brentuximab vedotin in combination with rituximab in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) (Part B) as well as further evaluate correlation of CD30 expression and response in DLBCL (Part C).

This trial is sponsored by Seattle Genetics. [1]

Study data

  • Condition: Non-Hodgkin Lymphoma
  • Interventions:
  • Phase: II
  • Enrollment: 176
  • Start: August 2011
  • Completion: June 2015
  • Last verified: June 2015

Study Schematic 

Screen Shot 2016-07-11 at 11.24.38 AM

Last Editorial review: July 11, 2016
Information based on (NIH/NCI) and other sources.