Linkers

Drug-Linker Complexes

What Are Drug-Linker Complexes?

Drug-linker complexes consist of two parts: a highly toxic drug which is a small molecule that interacts with intracellular...

What is Click Chemistry?

Click Chemistry has been used prominently in pharmaceutical and biotech R&D. It has become increasingly popular due its biocompatibility...

What does PEGylation Chemistry look like?

The introduction of a PEG linker to a molecule provides many benefits for pharmaceutical and biotech R&D due to...

What are the advantages of using monodisperse PEG in drug development?

Monodispersed PEG linkers are pure compounds with a single molecular weight. In contrast, polyPEG linkers contain variations in molecular...

What are PEG Peptides?

PEG Peptides are a featured class of PEG-linked peptides which can be used in antibody-drug conjugation (ADC).

What are PEG Linkers?

Hydrophilic poly(ethylene glycol) or PEG-linkers are particularly attractive as a linker for conjugation. Water solubility, lack of toxicity; low immunogenicity...

What are Stable Linkers?

Summary Linker Technologies Type of linkers used in the development of Antibody-drug Conjugates (ADC)s Stability of ADC in circulation Prominent...

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