What Are Customized ADCs?
As innovative next-generation immunotherapeutic agents, antibody-drug conjugates (ADCs) are being developed worldwide as a major strategy to combat cancer...
Antibody-drug Conjugate Development
Antibody-drug conjugates (ADCs) are a new implementation of an old idea: using antibodies to deliver toxic payloads directly to...
Characterization of Antibody-drug Conjugates
Antibody-drug conjugates (ADCs) represent a rapidly growing class of anti-cancer therapeutics in which a potent small molecule is linked...
Targeting Cancer with Antibody-drug Conjugates
Over the last two decades researchers have been able to significantly advance the molecular sophistication and clinical efficacy of antibody-drug...
What Are Biological Therapies For Cancer?
What is biological therapy? Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions...
What are targeted therapies?
What Is Targeted Therapy?
Targeted therapy is the foundation of precision medicine. It is a type of cancer treatment that...
What does a successful ADC look like?
A successful ADC is the one that works well in cancer patients with unmet medical needs where current approved...
What are the latest technologies being used to develop ADCs?
Targets
Most targets of ADC have unique requirements, including homogenous expression of ADC-accessible tumor surface antigens that internalize well and...
What is the clinical landscape for ADCs?
The clinical landscape of ADCs in both heme and solid cancers has grown to nearly 600 clinical trials incorporating...
What are the next generation ADCs?
In the last decade, there have unprecedented advances in discovery of new cytotoxic warheads of different mechanisms, new linkers...
