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The Review

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Characterization of Antibody-drug Conjugates

Antibody-drug conjugates (ADCs) represent a rapidly growing class of anti-cancer therapeutics in which a potent small molecule is linked...

Targeting Cancer with Antibody-drug Conjugates

Over the last two decades researchers have been able to significantly advance the molecular sophistication and clinical efficacy of antibody-drug...

What Are Biological Therapies For Cancer?

What is biological therapy? Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions...
Featured Image: Cancer cell Courtesy: © 2018. Fotolia. Used with permission.

What are targeted therapies?

What Is Targeted Therapy? Targeted therapy is the foundation of precision medicine. It is a type of cancer treatment that...

What is Click Chemistry?

Click Chemistry has been used prominently in pharmaceutical and biotech R&D. It has become increasingly popular due its biocompatibility...

What does PEGylation Chemistry look like?

The introduction of a PEG linker to a molecule provides many benefits for pharmaceutical and biotech R&D due to...

What are the advantages of using monodisperse PEG in drug development?

Monodispersed PEG linkers are pure compounds with a single molecular weight. In contrast, polyPEG linkers contain variations in molecular...

What does a successful ADC look like?

A successful ADC is the one that works well in cancer patients with unmet medical needs where current approved...

What are the latest technologies being used to develop ADCs?

Targets Most targets of ADC have unique requirements, including  homogenous expression of ADC-accessible tumor surface antigens that internalize well and...

What is the clinical landscape for ADCs?

The clinical landscape of ADCs in both heme and solid cancers has grown to nearly 600 clinical trials incorporating...

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