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Anti-CD205 Antibody-Drug Conjugate MEN1309/OBT076 Shows Substantial in vitro Antitumor Activity

Non-clinical study findings published in the journal Molecular Cancer Therapeutics describing the characterization of the anti-CD205 antibody-drug conjugate (ADC)...
WuXi Biologics Conjugation Solution Center

WuXi Biologics Expands Integrated Biologics Conjugation Solution Center

WuXi Biologics ("WuXi Bio") (2269.HK), a leading global open-access biologics technology platform company offering end-to-end solutions for biologics discovery,...
Featured Image: Cancer cell Courtesy: © 2018. Fotolia. Used with permission.

FDA Grants Accelerated Approval of Polatuzumab Vedotin in Select Patients

The U.S. Food and Drug Administration (FDA) today confirmed that it has granted accelerated approval of polatuzumab vedotin-piiq (Polivy™;...
General views from the 2019 Annual Meeting of the American Society (ASCO), held May 31 - June 4, 2019. Courtesy © ASCO/Phil McCarten 2019.

RC48-ADC Demonstrates Clinically Meaningful Results in HER2+ Metastatic and Unresectable Urothelial Cancer

Clinically meaningful topline results for a Phase II clinical trial of RC48-ADC were presented during the annual meeting of...
Unlocking ADC Manufacturing Innovation with ADC Bio

Webinar: Predicting And Lowering The Cost Of Antibody Drug Conjugates

ADC Bio and Biopharm will be hosting a live webinar titled, "Predicting and Lowering the Cost of Antibody Drug...

Three U.S. Companies Awarded MilliporeSigma’s Advance Biotech Grant

MilliporeSigma Awards Grants to Biotechs Focused on Traumatic Brain Injury, Vaccine Development and Chronic Pain. MilliporeSigma today announced the...
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ADC Therapeutics Expands Agreement with Synaffix

The Netherlands-based biotechnology company Synaffix, which develops clinical-stage technologies for the development of best-in-class antibody-drug conjugates or ADCs, confirmed...
Featured Image: Pellicon® Capsule. Courtesy: © 2019 MilliporeSigma. Used with permission.

Download the Application Note on the Pelicon® Capsule

Tangential flow filtration (TFF) is essential in the manufacturing of antibody drug conjugates (ADCs). Ultrafiltration (UF) is used to...

Depatuxizumab Mafodotin Did Not Demonstrate Survival Benefit in INTELLANCE-1 Study

Depatuxizumab mafodotin (also known as Depatux-M, and previously known as ABT-414), an antibody-drug conjugate (ADC) being developed by AbbVie,...
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Site Specific Conjugation of Hydrophobic Payloads Without Genetic Engineering

Site-specific conjugation leads to more homogeneous conjugates and allows control of the site of drug attachment. This approach frequently...

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