Must Read Articles

Antibody-drug conjugates: Recent Advances in Conjugation and Linker Chemistries

Authors: Tsuchikama K , An Z Title: Antibody-drug conjugates: recent advances in conjugation and linker chemistries. Published in: Protein Cell. 2016...

CD30 and CD30-Targeted Therapies in Hodgkin Lymphoma and Other B cell Lymphomas

Authors: Bhatt G∗, Maddocks K∗ Christian B∗ Published in: Curr Hematol Malig Rep. 2016 Sep 9. Abstract Evolution of cancer therapeutics has...

The flexibility of a generic LC-MS/MS method for the quantitative analysis of therapeutic proteins...

Authors: Lanshoeft C*, Wolf T**, Walles M**, Barteau S**, Picard F**, Kretz O**, Cianférani S***, Heudi O**** Published in: J...

Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology

Authors: Ogitani Y∗, Abe Y∗, Iguchi T∗, Yamaguchi J∗, Terauchi T∗, Kitamura M∗, Goto K∗, Goto M∗, Oitate M∗,...
Pills

Innovation in non-Hodgkin lymphoma drug discovery: What needs to be done?

Authors: Witkowska M, Smolewski P, Majchrzak A, Robak T Published in: Expert Opin Drug Discov. 2016 Aug 27. Abstract A new generation...

Second-Generation of Tunable pH-Sensitive Phosphoramidate-Based Linkers for Controlled Release

Authors: Choy CJ, Ley CR, Davis AL, Backer BS, Geruntho JJ, Clowers BH, Berkman CE. Published in: Bioconjug Chem. 2016...
Healthcare And Medicine. Doctor using a digital tablet

Antibody-drug Conjugates and Mechanisms of Resistance

An article published in the December 2016 issue of Molecular Cancer Therapeutics by Frank Loganzo, Matthew Sung and Hans-Peter...
Leukemia

Tumour cell surface antigen targeted therapies in B-cell lymphomas: Beyond rituximab.

Authors: Aku M, Chong G, Hawkes EA. Published in: Blood Rev. 2016 Aug 12. pii: S0268-960X(16)30051-0. doi: 10.1016/j.blre.2016.08.001. Abstract Recent proliferation of...
IgG1 monoclonal antibody (immunoglobulin)

Strategies of Targeting the Extracellular Domain of RON Tyrosine Kinase Receptor for Cancer Therapy...

Authors: Zarei O, Benvenuti S, Ustun-Alkan F, Hamzeh-Mivehroud M, Dastmalchi S. Title: Strategies of targeting the extracellular domain of RON...

Effects of Antibody, Drug and Linker on the Preclinical and Clinical Toxicities of Antibody-drug...

Authors: Donaghy H. Title: Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates Published in:...

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