Trastuzumab Emtansine in Treating Older Patients With Human Epidermal Growth Factor Receptor 2-Positive Stage I-III Breast Cancer (NCT02414646)
This phase II trial studies how well ado-trastuzumab emtansine (T-DM1, Kadcyla®; Genentech, Inc.) works in treating older patients with human epidermal growth factor receptor 2 (HER2)-positive stage I-III breast cancer. HER2 is a protein found on the surface of cancer cells that helps them to grow and spread. Trastuzumab emtansine may kill cancer cells by binding to HER2-positive on the surface of the tumor cells and blocking their ability grow and spread.
- Estrogen Receptor Negative
- HER2 Positive Breast Carcinoma
- Progesterone Receptor Negative
- Stage IB Breast Cancer
- Stage IIA Breast Cancer
- Stage IIB Breast Cancer
- Stage IIIA Breast Cancer
- Stage IIIC Breast Cancer
- Phase: II
- Estimated Enrollment: 200
- Start: May 2015
- Estimated Primary Completion: June 2020
- Last verified: July 2015
Last Editorial review: July 28, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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