Brentuximab Vedotin Followed by ABVD in Patients With Previously Untreated Hodgkin Lymphoma (NCT02275598)
The purpose of this study is to assess the efficacy of two three-weekly 1.8 mg/kg brentuximab vedotin administrations in untreated patients with Hodgkin Lymphoma (HL).
In this trial, treatment with the antibody-drug conjugate brentuximab vedotin is followed with the standard ABVD regimen, a combination of 4 chemotherapy drugs (doxorubicin, bleomycin, vinblastine, and dacarbazine) which was developed in the early 1970’s as an alternative to MOPP (mechlorethamine, vincristine, procarbazine and prednisone). The MOPP regimen was first combination regimen for the treatment of Hodgkin’s disease developed in 1964 by researchers at the National Cancer Institute.
- Condition: Hodgkin Lymphoma
- Drugs used in this trial
- Phase: II
- Enrollment: 12
- Start: April 2013
- Estimated Completion: March 2015
- Last verified: October 2014
Last Editorial review: July 18, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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