Patients With Brain Metastases From HER2-positive Breast Cancer (BIRTH) (NCT02135159)
The purpose of this study is to determine the optimal sequences of combined ado-trastuzumab emtansine (T-DM1, Kadcyla®; Genentech, Inc.) and whole-brain radiotherapy in patients presenting brain metastases from HER2-positive breast cancer in terms of acute toxicities and blood/cerebrospinal fluid T-DM1 pharmacokinetics.
This trial is sponsored by Institut du Cancer de Montpellier – Val d’Aurelle. (Montpellier Institute for Cancer) 
- Condition: HER2-positive Breast Cancer
- Phase: I
- Estimated Enrollment: 36
- Start: February 2014
- Estimated Completion: March 2017
- Last verified: May 2014
Last Editorial review: July 31, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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