Immunotherapy Following Reduced Intensity Conditioning and Allogeneic Stem Cell Transplant for Poor Risk CD30+ Hodgkin Lymphoma Patients (NCT02098512)
Patients with relapsed or refractory Hodgkin Lymphoma (HL) who are CD30+ will receive a standard of care reduced intensity regimen and an allogeneic stem cell transplant (from another person, related or unrelated). Following recovery, patients will receive a medication called brentuximab vendotin (Adcetris®; Seattle Genetics. Also known as SGN35) which is targeted against CD30+ cells. The study hypothesis is that this treatment will be safe and well tolerated in children and young adults.
This trial is sponsored by New York Medical College. 
- Condition: Hodgkin Lymphoma
- Phase: I & II
- Estimated Enrollment: 20
- Start: March 2014
- Estimated Completion: December 2018
- Last verified: April 2015
Last Editorial review: July 16, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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