A Phase I/II Study Of Brentuximab Vedotin In Combination With Multi-Agent Chemotherapy As Front-Line Treatment In Patients With CD30 Positive Primary Mediastinal Large B-Cell, Diffuse Large B-Cell, And Grey Zone Lymphomas (NCT01994850)
This is a Phase I/II multicenter single arm non-randomized open label study of the investigational drug, brentuximab vedotin, given in combination with routine chemotherapy (rituximab, cyclophosphamide, doxorubicin and prednisone) every 3 weeks for a total of 6 cycles.
This trial is sponsored by Abramson Cancer Center of the University of Pennsylvania. 
- CD30 Positive Primary Mediastinal Large B-cell Lymphom
- CD30 Positive Diffuse Large B-cell Lymphoma
- CD30 Positive Grey Zone Lymphoma
- Phase: I & II
- Estimated Enrollment: 32
- Start: November 2013
- Estimated Completion: November 2018
- Last verified: January 2015
Last Editorial review: July 16, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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