Study Title
Temsirolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma (NCT01902160)

Trial description
This phase I trial studies the side effects and best dose of temsirolimus when given together with brentuximab vedotin (also known as SGN-035) in treating patients with Hodgkin lymphoma that has returned or has not responded to treatment. Temsirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as brentuximab vedotin, may stimulate the immune system in different ways and stop cancer cells from growing. Giving temsirolimus with brentuximab vedotin may work better in treating patients with Hodgkin lymphoma.

This trial is sponsored by the National Cancer Institute (NCI). [1]

Study Data

  • Condition: Lymphoma
  • Interventions:
  • Laboratory Biomarker Analysis
  • Phase: I
  • Estimated Enrollment: 3
  • Start: September 2013
  • Estimated Primary Completion: June 2016 (Final data collection date for primary outcome measure)
  • Last verified: November 2015

Study Schemata


Last Editorial review: July 16, 2016
Information based on (NIH/NCI) and other sources.

Copyright © 2015 InPress Media Group. All rights reserved. Republication or redistribution of InPress Media Group content, including by framing or similar means, is expressly prohibited without the prior written consent of InPress Media Group. InPress Media Group shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. ADC Review / Journal of Antibody-drug Conjugates is a registered trademarks and trademarks of InPress Media Group around the world.

Add to Flipboard Magazine.