Temsirolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma (NCT01902160)
This phase I trial studies the side effects and best dose of temsirolimus when given together with brentuximab vedotin (also known as SGN-035) in treating patients with Hodgkin lymphoma that has returned or has not responded to treatment. Temsirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as brentuximab vedotin, may stimulate the immune system in different ways and stop cancer cells from growing. Giving temsirolimus with brentuximab vedotin may work better in treating patients with Hodgkin lymphoma.
This trial is sponsored by the National Cancer Institute (NCI). 
- Condition: Lymphoma
- Laboratory Biomarker Analysis
- Phase: I
- Estimated Enrollment: 3
- Start: September 2013
- Estimated Primary Completion: June 2016 (Final data collection date for primary outcome measure)
- Last verified: November 2015
Last Editorial review: July 16, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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