Study Title
Brentuximab Vedotin Combined With AVD Chemotherapy and Involved-Site Radiotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma (NCT01868451)
Trial Description
The purpose of this study is to find out whether brentuximab vedotin with AVD chemotherapy and radiation is a safe and effective treatment. It is hoped that this treatment will improve the ability to cure more patients with HL.
This trial is sponsored by Memorial Sloan Kettering Cancer Center [1]
Study Data
- Condition: Hodgkin Lymphoma
- Interventions:
- Drugs used in this trial
- Brentuximab Vedotin (Adcetris®; Seattle Genetics, Inc.)
- Doxorubicin (Doxil®; TTY Bio pharmacy Company Limited)
- Vinblastine (Generic; APP Pharmaceuticals, LLC)
- Filgrastim (Neupogen®; Amgen)
- Device: Dacarbazine
- Radiation: Involved-Site Radiation Therapy (ISRT)
- Procedure: Interim PET
- Interim PET Drug: Filgrastim (Neupogen®; Amgen)
- Drugs used in this trial
- Phase: 0
- Estimated Enrollment: 59
- Start: May 2013
- Estimated Completion: May 2016
- Last verified: May 2015
Study Schematic
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Last Editorial review: July 10, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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