Ado-Trastuzumab Emtansine in Treating Patients With HER2-Positive Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed by Surgery (NCT01816035)
This phase I trial studies the side effects and best way of giving ado-trastuzumab emtansine (T-DM1, Kadcyla®; Genentech, Inc.) in treating patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer that has spread to other parts of the body or nearby tissue and cannot be removed by surgery. Biological therapies, such as ado-trastuzumab emtansine, may stimulate the immune system in different ways and stop cancer cells from growing.
- HER2/Neu Positive Breast Cancer
- Recurrent Breast Carcinoma
- Stage IIIB Breast Cancer
- Stage IIIC Breast Cancer
- Stage IV Breast Cancer
- Phase: I
- Estimated Enrollment: 20
- Start: June 2014
- Estimated Primary Completion: February 2016
- Last verified: June 2015
Last Editorial review: July 28, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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