ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas (NCT01777152)
This is a double-blind, randomized, multicenter, phase III clinical trial to compare the efficacy and safety of brentuximab vedotin in combination with CHP with the standard-of-care CHOP in patients with CD30-positive mature T-cell lymphomas (MTCL) also known as peripheral T-cell lymphomas (PTCL).
Brentuximab vedotin is approved in select countries for the treatment of specific hematologic cancers after the failure of previous therapies, however its use in frontline mature T-cell lymphomas (MTCL) patients is strictly investigational.
- Anaplastic Large Cell Lymphoma (ALCL)
- T-Cell Lymphoma
- Non-Hodgkin Lymphoma (NHL)
- Phase: III
- Estimated Enrollment: 450
- Start: January 2013
- Estimated Completion: December 2019
- Last verified: June 2015
Last Editorial review: July 15, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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