NCT01777152 (ECHELON-2) (CLINICAL TRIAL / BRENTUXIMAB VEDOTIN / SGN-035 / ADCETRIS®)

Study Title
ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas (NCT01777152)

Trial Description
This is a double-blind, randomized, multicenter, phase III clinical trial to compare the efficacy and safety of brentuximab vedotin in combination with CHP with the standard-of-care CHOP in patients with CD30-positive mature T-cell lymphomas (MTCL) also known as peripheral T-cell lymphomas (PTCL).

Brentuximab vedotin is approved in select countries for the treatment of specific hematologic cancers after the failure of previous therapies, however its use in frontline mature T-cell lymphomas (MTCL) patients is strictly investigational.

This trial is sponsored by Millennium PharmaceuticalsSeattle Genetics. [1]

Study Data

Study Schematic

NCT01777152 (ECHELON-2) (CLINICAL TRIAL / BRENTUXIMAB VEDOTIN / SGN-035 / ADCETRIS®)

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Last Editorial review: July 15, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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