NCT01691898 (Clinical Trial / DCDT2980S / Pinatuzumab Vedotin / RG-7593)

Study Title
A Study of DCDT2980S in Combination With MabThera/Rituxan or DCDS4501A in Combination With MabThera/Rituxan and Evaluation of Combination DCDS4501A and Obinutuzumab in Patients With Non-Hodgkin’s Lymphoma (NCT01691898)

Trial Description
This randomized, multicenter, open-label study will evaluate the safety and the efficacy of DCDT2980S (pinatuzumab vedotin or RG-7593) in combination with MabThera/Rituxan (rituximab) or DCDS4501A (polatuzumab vedotin or RG-7596) in combination with MabThera/Rituxan, as well as a combination of DCDS4501A with obinutuzumab in patients with relapsed or refractory follicular non-Hodgkin’s lymphoma and relapsed/refractory diffuse large B-cell lymphoma.

This trial is sponsored by Genentech, Inc. [1]

Study Data

  • Condition:
    • Follicular Lymphoma
    • B-Cell Lymphoma
  • Interventions:
    • Drugs used in this trial
      • DCDS4501A (polatuzumab vedotin or RG-7596; Genentech)
      • DCDT2980S (pinatuzumab vedotin or RG-7593; Genentech)
      • obinutuzumab (Gazyva®,Genentech, Inc.)
      • rituximab (Rituxam®; Biogen, Inc,/ Genentech, Inc.)
  • Phase: II
  • Estimated Enrollment: 226
  • Start: September 2012
  • Estimated Completion: June 2019
  • Last verified: July 2015

Study Schematic

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Last Editorial review: July 13, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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