A Study of Escalating Doses of DCDS4501A in Patients With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and DCDS4501A in Combination With Rituximab in Patients With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma (NCT01290549)
This is a Phase I, multicenter, open-label, dose-escalation study of DCDS4501A (also known as polatuzumab vedotin or RG-7596) administered as a single agent by IV infusion to patients with relapsed or refractory hematologic malignancies. In Phase Ib, patients will receive DCDS4501A in combination with rituximab.
This trial is sponsored by Genentech.
- Non-Hodgkin’s Lymphoma
- Chronic Lymphocytic Leukemia
- Phase: I
- Enrollment: 95
- Start: March 2011
- Primary Completion: June 2012
- Last verified: February 2015
Last Editorial review: July 13, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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