NCT00833963 (MotHER) (Clinical Trial/ Ado-Trastuzumab Emtansine)

Study Title
An Observational Study of Pregnancy And Pregnancy Outcomes in Women With Breast Cancer Treated With Herceptin, Perjeta In Combination With Herceptin, or Kadcyla During Pregnancy or Within 7 Months Prior To Conception (MotHER) (NCT00833963)

Trial Description
The MotHER Pregnancy Registry is a U.S.-based, prospective, observational cohort study in women with breast cancer who have been or are being treated with trastuzumab (Herceptin®;Genentech, Inc.) plus perjeta with or without pertuzumab, or ado-trastuzumab emtansine (T-DM1, Kadcyla®; Genentech, Inc.), during pregnancy or within 7 months prior to conception (regardless of cancer stage at the time of trastuzumab, pertuzumab, or ado-trastuzumab emtansine exposure).

This trial is sponsored by Genentech, Inc. [1]

Study Data

  • Condition:
    • Breast Cancer
    • Pregnancy
  • Interventions:
  • Phase: IV
  • Estimated Enrollment: 100
  • Start: December 2008
  • Estimated Completion: December 2022
  • Last verified: October 2014

Study Schematic

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Last Editorial review: July 31, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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