NCT00354107 (CLINICAL TRIAL / BRENTUXIMAB VEDOTIN / SGN-035 / ADCETRIS®)

Study Title
Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma (NCT00354107)

Trial Description
This phase I/II trial is studying the side effects and best dose of SGN-30 when given together with ifosfamide, carboplatin, and etoposide and to see how well they work in treating young patients with recurrent anaplastic large cell lymphoma. Drugs used in chemotherapy, such as ifosfamide, carboplatin, and etoposide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.

Monoclonal antibodies, including antibody-drug conjugates such as SGN-30, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them.

This trial is sponsored by National Cancer Institute (NCI). [1]

Study Data

  • Condition: 
    • Anaplastic Large Cell Lymphoma
    • Recurrent Childhood Anaplastic Large Cell Lymphoma
  • Interventions:
  • Phase: I & II
  • Enrollment: 5
  • Start: January 2007
  • Completion: January 2010
  • Last verified: October 2011

Study Schematic

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Last Editorial review: July 17, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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