Gemtuzumab Ozogamicin and Cyclosporine in Treating Older Patients With Relapsed Acute Myeloid Leukemia (NCT00089050)
Monoclonal antibodies, including antibody-drug conjugates such as gemtuzumab ozogamicin (Mylotarg®; Pfizer/Wyeth-Ayerst Laboratories), can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells cyclosporine (Neoral®; Novartis Pharmacueticals Co.) may increase the effectiveness of gemtuzumab ozogamicin by making cancer cells more sensitive to the drug. Combining gemtuzumab ozogamicin with cyclosporine may kill more cancer cells.
This phase II trial is studying how well giving gemtuzumab ozogamicin together with cyclosporine works in treating older patients with relapsed acute myeloid leukemia.
This trial is sponsored by Fred Hutchinson Cancer Research Center. 
- Condition: Leukemia
- Phase: II
- Start: May 2004
- Completion: March 2006
- Last verified: November 2011
Last Editorial review: July 22, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.
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